The objective of this article is to review research works carried for development of topical biodegradable dermal patch including a biodegradable biopolymers to accelerate wound healing. Delays occurred in acute cutaneous wound healing leads to local infections, and transition toward chronic and non-healing wounds. Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. The aim of this study is to hasten and improve the wound healing activity. Topical applications of compounds with free radical scavenging properties have shown to improve wound healing significantly and protect tissues from oxidative damage. Natural polymers are preferred candidates for designing wound healing patches of therapeutic drugs in treatment of different types of ailments. Chitosan collagen and gelatin are few important biodegradable ingredients that find place in wound healing formulation designing and technology. The polymers that render wound healing properties, the combination of such polymers display desired results.
Loading....